The Basics
What is
Magnesium glycinate?
Magnesium glycinate (also called magnesium bisglycinate) is a form of magnesium supplement in which magnesium is chemically bound to glycine, an amino acid. The two names refer to the same compound and are used interchangeably. Magnesium is involved in more than 300 enzymatic reactions in the body: energy production, nerve and muscle signaling, blood sugar regulation, bone formation, and the maintenance of normal heart rhythm.
Two active components: The magnesium supports hundreds of physiological systems. Glycine functions as an inhibitory neurotransmitter, upporting the conditions that allow the nervous system to settle toward a calmer baseline but the extent to which the glycine ligand contributes to clinical effects independently of magnesium bisglycinate is not well established.
Magnesium glycinate is specifically chosen because it is well-tolerated by the digestive system, making it practical for consistent, long-term daily use, unlike oxide or citrate forms, which can have a laxative effect at higher doses, though GI side effects can still occur and vary by dose and formulation